New Step by Step Map For cees dekker
New Step by Step Map For cees dekker
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‘Certainly, which is about ideal. I look for a Actual physical understanding of biological units inside a bottom-up way. I feel you could distinguish 3 traces of investigate in my group in the intervening time. The very first worries chromosome composition: how do you obtain a metre-very long DNA polymer folded and organised in this kind of microscopic mobile? We've designed visualisation procedures that enable us to review how, such as, SMC proteins loop DNA (online video on Youtube) to be able to Create up chromosomes.
Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transportation of macromolecules
Around the exact time, the group of Paul McEuen, who was then based within the University of California, Berkeley, confirmed related outcomes on ropes of bundled nanotubes. Depending on the wrapping angle, nanotubes can can be found in metallic or semiconducting variants, a prediction that we and Charles Lieber’s group at Harvard College independently confirmed working with scanning tunnelling spectroscopy experiments.
2007, to start with genuine-time detection of strand Trade in homologous recombination by RecA; discovery of the minimal persistence duration of ends of microtubules; and solved the system of biosensing with carbon nanotubes
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Experimental section diagram of negatively supercoiled DNA measured by magnetic tweezers and fluorescence,
MATLAB codes for data processing are offered at . Julia codes utilized for numerical simulation are available at .
2000, discovery that nanotubes can have extraordinary huge latest densities; resolved the controversial situation of Digital transportation by means of DNA molecules by measurements of insulating habits at the single molecule degree; and demonstration of the AFM system for solitary-molecule manipulation of nanotubes
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‘The fantastically refined way through which factors in nature functionality hardly ever ceases to amaze me. If we clear up the puzzle of how daily life came into remaining, I be expecting that my amazement with the complexity https://www.ceesdekker.net of creation will have greater and with it my awe for that greatness in the Creator.’
Due to the fact 2000 he moved to single-molecule biophysics and nanobiology, with investigation from studies of DNA loop extrusion and supercoiling to DNA translocation by way of nanopores. Extra not too long ago his exploration has focused on learning chromatin framework and mobile division with bacteria on chip, even though he is usually attempting to eventually build synthetic cells from the bottom up.
Nanoscientist Cees Dekker is really an amiable and flamboyant male who appears A lot younger when compared to the sixty two several years he truly is – fashionable Eyeglasses, psychedelic shirt, participating smile – but not one to squander time. He normally takes his time, but no more than vital.
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Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij achieved enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond intelligent layout in 2005. (nl)